The major goal of this project is the isolation and identification of new natural products applying NMR and computational methods to elucidate their structures, including the relative and absolute configuration as already described in the first application. The distance geometry approach will be extended to include RDCs since it is most suited for constitutionally diverse molecules. This, and the possibility for enantiomer differentiating alignment may ultimately lead to the determination of absolute configurations.
DFG Programme
Research Units
Major Instrumentation
1.7 mm probe for 400 NMR spectrometer
Instrumentation Group
1740 Hochauflösende NMR-Spektrometer