Project Details
Common resources of the research unit
Applicant
Professor Dr. Andreas Zimmer
Subject Area
Biological Psychiatry
Term
from 2008 to 2016
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 42860621
Final Report Year
2017
Final Report Abstract
The main task of CP2 was the establishment of animal colonies providing genetic mouse models for all investigators in the Research Unit. CP 2 also provided administrative support and facilitated scientific exchange within the Research Unit by organizing regular meetings and workshops.
Publications
- (2013). Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice. J Mol Cell Cardiol, 66:126-132
Hoyer FF, Khoury M, Slomka H, Kebschull M, Lerner R, Lutz B, Schott H, Lütjohann D, Wojtalla A, Becker A, Zimmer A, Nickenig G
(See online at https://doi.org/10.1016/j.yjmcc.2013.11.013) - (2013). Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory. Front Aging Neurosci. Epub 2012 Dec 5
Albayram O, Bilkei-Gorzo A, Zimmer A
(See online at https://doi.org/10.3389/fnagi.2012.00034) - (2014). Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging, 36:710-719
Schmöle AC, Lundt R, Ternes S, Albayram O, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A
(See online at https://doi.org/10.1016/j.neurobiolaging.2014.09.019) - (2014). CB2 receptor-mediated effects of pro-inflammatory macrophages influence survival of cardiomyocytes. Life Sci, 138 (2015) 18-28
Heinemann JC, Duerr GD, Keppel K, Breitbach M, Fleischmann BK, Zimmer A, Wehner S, Welz A, Dewald O
(See online at https://doi.org/10.1016/j.lfs.2014.11.027) - (2014). The CB1 Receptor as an Important Mediator of Hedonic Reward Processing. Neuropsychopharmacology, 39(10):2387-96
Friemel CM, Zimmer A, Schneider M
(See online at https://doi.org/10.1038/npp.2014.86) - (2014). The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. Basic Res Cardiol, 109(4):425
Duerr GD, Heinemann JC, Suchan G, Kolobara E, Wenzel D, Geisen C, Matthey M, Passe-Tietjen K, Mahmud W, Ghanem A, Tiemann K, Alferink J, Burgdorf S, Buchalla R, Zimmer A, Lutz B, Welz A, Fleischmann BK, Dewald O
(See online at https://doi.org/10.1007/s00395-014-0425-x) - (2015). Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. Biomed Res Int, 2015:456582
Gestrich C, Duerr GD, Heinemann JC, Meertz A, Probst C, Roell W, Schiller W, Zimmer A, Bindila L, Lutz B, Welz A, Dewald O
(See online at https://doi.org/10.1155/2015/456582) - (2015). Enhanced microglial activity in FAAH-/- animals. Life Sci, 138:52-56
Ativie F, Albayram O, Bach K, Pradier B, Zimmer A, Bilkei-Gorzo A
(See online at https://doi.org/10.1016/j.lfs.2014.12.016) - (2015). Inhibition of FAAH reduces nitroglycerin-induced migraine-like pain and trigeminal neuronal hyperactivity in mice. Eur Neuropsychopharmacol, 25(8):1388-96
Nozaki C, Markert A, Zimmer A
(See online at https://doi.org/10.1016/j.euroneuro.2015.04.001) - (2016). Lack of hippocampal CB1 receptor desensitization by Δ(9)-tetrahydrocannabinol in aged mice and by low doses of JZL 184. Naunyn Schmiedebergs Arch Pharmacol. 389(6):603-12
Feliszek M, Bindila L, Lutz B, Zimmer A, Bilkei-Gorzo A, Schlicker E
(See online at https://doi.org/10.1007/s00210-016-1226-6)