Circuit-specific improvements of mnemonic discrimination in the rodent and human entorhino-hippocampal subnetworks (B07*)

Subject Area Molecular Biology and Physiology of Neurons and Glial Cells
Human Cognitive and Systems Neuroscience
Term since 2025
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 425899996
 

Project Description

We hypothesize that the neural resources for spatial and non-spatial memory can be selectively mobilised in a network-specific manner. Our research strategy consists in targeting distinct entorhino-hippocampal subnetworks, deploying exogenous (Deep Brain Stimulation, optogenetics) and endogenous stimulation (cognitive training) using a cross-species approach and, characterising at the single-cell and whole-brain levels the physiological mechanisms underlying this mobilisation.
DFG Programme Collaborative Research Centres
Subproject of SFB 1436:  Neural resources of cognition
Applicant Institution Otto-von-Guericke-Universität Magdeburg
Project Heads Professor Dr. Frank Angenstein; Davide Ciliberti, Ph.D.; Professorin Dr. Magdalena Sauvage