From Protein Adsorption to Crystallisation Tuned by Multivalent Ions (PATMI 2.0)

• Applicant: Professor Dr. Frank Schreiber
• Subject Area: Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
• Term: since 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 553108211

This research project delves into the relationship between protein adsorption and crystallization, with a focus on multivalent ions' influence. Divided into specific work packages, the study aims to understand the kinetics and mechanisms of nucleation at interfaces. Key questions involve the impact of bulk phase behavior, interface properties, and the conversion process from adsorption to crystallization. Utilizing advanced techniques such as QCM-D, ellipsometry, neutron / X-ray reflectometry, and GIXD, the project aims to unravel the complexities of protein behavior at interfaces. This project promises valuable insights into protein interactions and nucleation phenomena.

• DFG Programme: Research Grants
• Co-Investigators: Dr. Alexander Gerlach; Privatdozent Fajun Zhang, Ph.D.