Regulation of splicing fidelity in response to DNA double-strand breaks
(A05)
Subject Area
Cell Biology
Term
since 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 520471345
This project aims to explore the complex interplay between DNA double-strand breaks and the fidelity of RNA splicing. DNA double-strand breaks trigger complex cellular responses, impacting gene expression and splicing processes. The research will delve into how DSBs impact the accuracy of splicing, examining aspects such as chromatin architecture at breaks, the role of the spliceosome, and genome-wide effects on RNA production.
DFG Programme
Collaborative Research Centres