Function of arginine methylation in post-transcriptional gene regulation

• Applicant: Professorin Dr. Antje Ostareck-Lederer
• Subject Area: Cell Biology
• Term: from 2005 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5441006

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Asymmetric arginine dimethylation of hnRNP K by PRMT1 inhibits its interaction with c-Src. (2006) J. Biol. Chem. 281, 11115-11125
  Ostareck-Lederer, A., Ostareck, D.H., Rücknagel, K.P., Schierhorn, A., Moritz, B., Hüttelmaier, S., Flach, N., Handoko, L. and Wahle, E.
  
• The DICE-binding activity of KH domain 3 of hnRNP K is affected by c-Src mediated tyrosine phosphorylation. (2006) J. Mol. Biol. 361, 470-481
  Messias, A., Harnisch, C., Ostareck-Lederer, A., Sattler, M. and Ostareck, D.H.
  
• Deciphering the crosstalk between hnRNP K and c-Src: The c-Src activation domain in hnRNP K is distinct from the site of interaction. (2007) Mol. Cell. Biol. 27, 1758-1770
  Adolph, D., Flach, N., Müller, K., Ostareck, D.H. and Ostareck-Lederer, A.
  
• mRNA silencing in human erythroid cell maturation: hnRNP K controls the synthesis of its regulator c-Src. (2008) J. Biol. Chem., 283, 18461-18472
  Naarmann, I., Harnisch, C., Flach, N., Kremmer, E., Kühn, H., Ostareck, D.H. and Ostareck-Lederer, A.
  
• Promiscuous modification of the nuclear poly(A) binding protein by multiple protein arginine methyl transferases does not affect the aggregation behaviour. (2008) J. Biol. Chem. 283, 20408-20420
  Fronz, K., Otto, S., Kölbel, K., Kühn, U., Friedrich, H., Schierhorn, A., Beck-Sickinger, A., Ostareck-Lederer, A. and Wahle, E.