Untersuchung des inhibitorischen Einflusses pro-inflammatorischer Mediatoren auf die Signalvermittlung von Zytokinen

• Applicant: Professor Dr. Johannes Georg Bode
• Subject Area: Gastroenterology
• Term: from 2004 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5439931

• Final Report Year: 2011

Final Report Abstract

No abstract available

Publications

• 2008. Influenza A virus inhibits type I IFN signaling via NF‐κB dependent induction of SOCS‐3 expression. PLoS Pathogens 4:e1000196
  Pauli, E., M. Schmolke, D. Viemann, J. Roth, J. G. Bode and S. Ludwig
  
• 2009. The hepatitis C virus non‐ structural 3/4A protease activates EGF‐induced signal‐transduction by cleavage of the T‐cell protein tyrosine phosphatase. Hepatology, 49, 1810‐1820
  Brenndörfer, E. D., J. Karthe, L. Frelin, P. Cebula, A. Erhardt, J. Schulte am Esch, H. Hengel, R. Bartenschlager, M. Sällberg, D. Häussinger, and J. G. Bode
  
• 2010. Anti tumor necrosis factor alpha treatment promotes apoptosis and prevents hepatocyte regeneration in a mouse model of chronic hepatitis C virus (HCV): a clue to its beneficial effects in HCV therapy. Hepatology, 52, 1553‐1563
  Brenndörfer, E.D., M. Weiland, L. Frelin, E. Derk, G. Ahlén, J. Jiao, J.G. Bode, M. Sällberg
  
• 2010. Cross‐regulation of cytokine signaling: Pro‐inflammatory cytokines restrict IL‐6 signalling through receptor internalisation and degradation. J Cell Sci, 123, 947‐959
  Radtke, S., S. Wüller, X. P. Yang, B. E. Lippok, B. Mütze, C. Mais, H. Schmitz‐van de Leur, J. G. Bode, M. Gästel, P. C. Heinrich, I. Behrmann, F. Schaper, and H. M. Hermans