Finer analysis of the HLA-DO inhibition of HLA-DM

• Applicant: Privatdozent Dr. Timo Burster
• Subject Area: Immunology
• Term: from 2004 to 2006
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5437530

During my one-year fellowship, I will map the residues that mediate DM/DO interaction through the generation and identification of DM mutants as well as DO mutants that impair the normal function of the DM/DO complex. In addition, kinetic studies will be performed to test the hypothesis that DO is a competitive inhibitor of DM.

• DFG Programme: Research Fellowships
• International Connection: USA