Ursprung und Diversität von Baculoviren
Final Report Abstract
The obtained results of the project can be considered as a milestone in the elucidation of the early evolution of baculoviruses and related so-called "non-occluded" baculoviruses or nudiviruses. For the phylogeny and evolution of baculoviruses the following main conclusions can be drawn form the project: • Different insect-specific dsDNA viruses, such as Heliothis zea virus -1 ( = HzNV-1), Gryllus bimaculatus NV and Oryctes rhinoceros NV shared a common ancestor and should be considered as members of the same genus or family of viruses, which need to be established by the International Committee on Taxonomy of Viruses (ICTV). • Therefore a new genus name (= Nudiviruses) comprising these three viruses is proposed to the scientific community. • Nudiviruses are phylogenetically related to baculoviruses. These viruses share a set of 15- 17 core genes, including structural genes and nucleotide metabolism, such as the DNA ploymerase and the subunits of the RNA polymerase. • viruses from different lineages (Baculoviruses and Nudiviruses, but eventually also including Nimaviruses and Salivary gland hypertrophy viruses) may form a super-group of phylogenetically related viruses sharing a common ancestor. • The proposed phylogeny of the baculoviruses and nudiviruses does not mirror the phylogeny of the insect hosts. Hence, the phylogenetic incongruence of viruses and their insect hosts suggests that host ecology rather than host phylogeny was the main driving force of nudivirus and baculovirus evolution.
Publications
- Yongjie Wang , Regina G. Kleespies, Monique van Oers, Barry Ale, Moslim B. Ramie, Trevor Jackson, Just Vlak, Johannes Jehle. Towards the complete genome sequence of the baculovirus-related nonoccluded Oryctes rhinoceros nudivirus of beetles. 401 annual meeting of the society for invertebrate pathology and 1st international forum on entomopathogenic nematodes and symbiotic bacteria. August 12 to 16, 2007, Quebec, Canada.
- Yongjie Wang and Johannes A. Jehle. Ancient diversification of baculovirus-related nonoccluded nudiviruses of insects. Deutsche Entomologentagung 2007, 26.2. - 1.3.2007, Innsbruck, Switzerland.
- Yongjie Wang, John P. Burand & Johannes A. Jehle. Nudivirus genomics: diversity and classification. Virologica Sinica. 2007, 22: 128-136.
- Yongjie Wang, Monique M. van Oers, Allan M. Crawford, Just M. Vlak & Johannes A. Jehle. Genomic analysis of Oryctes rhinoceros virus suggests genetic relationship to Heliothis zea virus 1. Archives of Virology. 2007, 152:519-531.
- Yongjie Wang, Monique M. van Oers, Allan M. Crawford, Just M. Vlak and Johannes A. Jehle. The partial genome sequence of Oryctes rhinoceros virus. 9lh International Colloquium on Invertebrate Pathology and Microbial Control, 39th annual Meeting of the SIP and 81 International Conference on Bacillus thuringiensis, August 27 to September 1, 2006, Wuhan, China.
- Yongjie Wang, Regina G. Kleespies, Alois. Huger and Johannes A. Jehle. The genomic sequence of the Gryllus bimaculatus virus. 9th International Colloquium on Invertebrate Pathology and Microbial Control, 39th annual Meeting of the SIP and 8th International Conference on Bacillus thuringiensis, August 27 to September 1, 2006, Wuhan, China.
- Yongjie Wang, Regina G. Kleespies, Alois. M. Huger & Johannes A. Jehle. The genome of the Gryllus bimaculatus virus indicates an ancient diversification of baculovirus-related non-occluded dsDNA nudiviruses of insects. Journal of Virology. 2007, 81:5395-5406.
