Rolle des Zytoskeletts bei der Endothel-Infektion durch S. aureus

• Applicant: Professor Dr. Martin Aepfelbacher
• Subject Area: Parasitology and Biology of Tropical Infectious Disease Pathogens
• Term: from 2002 to 2011
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5389377

• Final Report Year: 2010

Final Report Abstract

No abstract available

Publications

• Cytotoxic necrotizing factor 1 of Escherichia coli stimulates Rho/Rho-kinase-dependent myosin light-chain phosphorylation without inactivating myosin light-chain phosphatase in endothelial cells. Infect Immun. 2003 Sep;7l(9):5188-93
  Essler M, Linder S, Schell B, Hüfner K, Wiedemann A, Randhahn K, Staddon JM, Aepfelbacher M.
  
• Microviscoelasticity of the apical cell surface of human umbilical vein endothelial cells (HUVEC) within confluent monolayers. Biophys J. 2004 Aug;87(2): 1338-50
  Feneberg W, Aepfelbacher M, Sackmann E
  
• Live cell imaging of phagosome maturation in Staphylococcus aureus infected human endothelial cells: small colony variants are able to survive in lysosomes. Med Microbiol Immunol. 2006 Dec;195(4);] 85-94. Epub 2006 Apr 5
  Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M
  
• Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells. Mol Biol Cell. 2006 Dec;17(12):5198-210. Epub 2006 Oct 4
  Schröder A, Schröder B, Roppenser B, Linder S, Sinha B, Fässler R, Aepfelbacher M
  
• Effector functions of pathogenic Yersinia species. Review. Thromb Haemost. 2007 Sep;98(3):521-9
  Aepfelbacher M, Trasak C, Ruckdeschel K
  
• Yersinia enterocolitica differentially modulates RhoG activity in host cells. J Cell Sci. 2009 Mar 1;122(Pt 5):696-705. Epub 2009 Feb 10
  Roppenser B, Röder A, Hentschke M, Ruckdeschel K, Aepfelbacher M
  
• Epidemiology, variable genetic organization and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients. Microbiology. 2010 Mar;156(Pt3):860-72
  Franke GC, Böckenholt A, Sugai M, Rohde H, Aepfelbacher M