Project Details
Projekt
Innate immune training-mediated regulation of osteoclasts and inflammatory bone loss (C03)
Subject Area
Toxicology, Laboratory Medicine
Term
since 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 501752319
Project C03 will analyze whether trained immunity may also affect osteoclast generation and function and how this might contribute to inflammatory bone loss. The overarching theme and long-term perspective of C03 is to show that diseases related to inflammatory bone loss are associated with "trained" bone-marrow progenitors, poised towards enhanced osteoclastogenesis and hence identify trained immunity-associated therapeutic targets.
DFG Programme
CRC/Transregios
Applicant Institution
Friedrich-Alexander-Universität Erlangen-Nürnberg
Project Heads
Professor Dr. Triantafyllos Chavakis; Lydia Kalafati, Ph.D.
