Role for the c-type lectin receptor Dectin-1 (Clec7a) in inflammatory bone disease
(C02)
Subject Area
Dentistry, Oral Surgery
Immunology
Rheumatology
Term
since 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 501752319
Project C02 will delineate how Dectin-1 links infection to bone destruction using periodontitis as a prototype disease, in which chronic infection leads to bone loss. Overall, the project seeks to define a novel pathway that orchestrates bone destruction in the oral cavity with the long-term aim to identify risk populations of periodontitis patients that would profit from early anti-resorptive treatment.
DFG Programme
CRC/Transregios
