Mechanisms of Ion Channel Gating

• Applicant: Professor Dr. Ulf-Peter Hansen
• Subject Area: Plant Biochemistry and Biophysics
• Term: from 2000 to 2011
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5228782

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• 2004. Distributionsper-level: A means of testing level detectors and models of patch clamp data. J. Membrane Biol. 197: 49-58
  Schroeder, I., Huth, T., Suitchmezian, V., Jarosik, J., Schnell, S., Hansen, U.P.
  
• 2005. A subsequent fit of time series and amplitude histogram of patch clamp data reveals rate-constants up to 1 ms-1. J. Membrane Biol. 203: 83-99
  Schroeder, I., P. Harlfinger, P., Huth, T., Hansen, U.P.
  
• 2005: 4-Mode-Gating-Modell Modellierung der Inaktivierung des Natriumkanals. Dissertation Kiel
  Huth, Tobias
  
• 2006. Strengths and limits of Beta distributions as a means of reconstructing the true single-channel current in patch clamp time series with fast gating. J. Membrane Biol. 210: 199-212
  Schroeder, I., Hansen, U.P.
  
• 2006. The power of two-dimensional dwell-time analysis for model discrimination, temporal resolution, multichannel analysis and level detection. J. Membrane Biol. 214: 19-32
  Huth, T., Schroeder, I., Hansen, U.P.
  
• 2007. Saturation and ms-gating of current indicate depletion-induced instability of the MaxiK selectivity filter. J. Gen. Physiol. 130: 83-97
  Schroeder, I., Hansen, U.P.
  
• 2007: Improved sub-ms gating analysis indicates conformational changes as caused by ion/pore interactions in the MaxiK channel. Dissertation Kiel
  Schröder, Indra
  
• 2008. 4-mode gating model of the inactivation of sodium channel Nav1.2a. Pflügers Archiv
  Huth, T., Schmidtmayer, J., Alzheimer, C., Hansen, U.P.
  
• 2008. TI+-induced ms-gating of current indicates instability of the MaxiK selectivity filter as caused by ion/protein interaction. J. Gen. Physiol.
  Schroeder, I., Hansen, U.P.