Project Details
Effector-induced manipulation of host polyamine levels (B03)
Subject Area
Organismic Interactions, Chemical Ecology and Microbiomes of Plant Systems
Term
since 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 491090170
This project aims at investigating how the Ralstonia solanacearum transcription activator-like effector (TALE) protein Brg11 promotes bacterial disease by manipulation of host polyamine levels and derived metabolites. Specifically, we want to elucidate how Brg11 manipulates metabolic diversity and how R. solanacearum benefits from these changes. At the technical level this projects aims to establish novel approaches that enable us to study the function of the R. solanacearum effector Brg11 specifically in root target cells rather than in bulk infected root tissue.
DFG Programme
CRC/Transregios
Applicant Institution
Ludwig-Maximilians-Universität München
Project Head
Professor Dr. Thomas Lahaye