Plasticity and biological relevance of organellar lipid codes
(P09)
Subject Area
Cell Biology
Biochemistry
Term
since 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 467522186
This project will focus on the functional consequences of and compensatory cellular responses to imbalances in organellar lipid codes caused by pathogenic variants of the sphingomyelin synthase SMS2. How mislocalization of this enzyme affects membrane lipid homeostasis in relation to extracellular vesicle formation by osteogenic cells and the implications in dysregulated bone formation will be addressed in detail.
DFG Programme
Collaborative Research Centres
