Dynamic manipulation of functional plasticity of the host cell endosomal system by an intracellular pathogen
(P08)
Subject Area
Cell Biology
Term
since 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 467522186
This project will explore how Salmonella as a facultative intracellular pathogen triggers alterations in the endomembrane system of its host to promote its replication. The project will reveal how Salmonella effector proteins are targeted to endosomal membranes to exploit the functional plasticity of the mammalian endosomal system, with a focus on the lipid composition of Salmonella-containing vacuoles (SCV). This analysis will reveal how Salmonella controls the biogenesis of its intracellular niche.
DFG Programme
Collaborative Research Centres
