Formation, composition and role of extracellular vesicles in the ischemic heart
(P02)
Subject Area
Cell Biology
Animal Physiology and Biochemistry
Developmental Biology
Term
since 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 467522186
This project takes advantage of an ischemia models in mice (Mus) and the highly regenerative spiny mice (Acomys) to ask how a specific population of extracellular vesicles (EV) at the plasma membrane of cardiac fibroblasts is formed and how these vesicles affect the activity of other cardiac cells. The project will analyze the EV composition their injury induced changes as well as their uptake and cardioprotective and/or angiogenic capacity in target cells.
DFG Programme
Collaborative Research Centres
