Age-dependent airway epithelial determinants of severe human respiratory viral infections (A01)

Subject Area Virology
Term since 2023
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 492620490
 

Project Description

A01 will focus on the link between age-specific cellular differentiation and immune function of the upper respiratory tract epithelium as well as viral entry, replication and spreading. The accessibility of candidate molecular decision points to modification and resulting consequences for the outcome of respiratory viral infections (RVIs), and microbiota-derived environmental cues impacting on the programming of molecular decision points in RVIs will be investigated.
DFG Programme Collaborative Research Centres
Subproject of SFB 1583:  Decisions in Infectious Diseases (DECIDE)
Applicant Institution Julius-Maximilians-Universität Würzburg
Project Heads Dr. Simone Backes; Professorin Dr. Dorothee Viemann