Project P09 will use modeling and simulations to gain a mechanistic understanding of fundamental regulatory processes. We will investigate the activation of the unfolded protein response (UPR), a pathway central in health and disease. We will establish artificial intelligence-guided simulations to understand how membrane-mediated interactions control the activation of the UPR. Furthermore, we will develop an interdisciplinary strategy to unravel the dimerization and activation of MET receptors.
DFG Programme
Collaborative Research Centres
