Role of anti-heart autoimmunity for disease progression in patients with acute decompensation of heart failure
(C05)
Subject Area
Cardiology, Angiology
Term
since 2022
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 453989101
We follow the overarching hypothesis that episodes of decompensated heart failure, i.e. acute heart failure (AHF), induce adaptive immune responses against myocardial antigens, thus contributing to heart failure progression and worsening prognoses. Hence, we aim to monitor the immune status, including occurrence and time course of anti-heart antibody titres as well as the prevalence of T-cells with reactivity towards de- fined cardiac antigens, in a well-characterized cohort of patients presenting with AHF.
DFG Programme
Collaborative Research Centres
