Predicting therapy response and relapse of aggressive B cell lymphomas
(C03*)
Subject Area
Evolutionary Cell and Developmental Biology (Zoology)
Term
since 2022
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 325931972
Project C3 will investigate molecular mechanisms that allow the diffuse large B cell lymphomas (DLBCL) to escape chemo-immune therapies. We will combine genotyping with spatial analysis of cancer tissues by new imaging and machine-learning techniques. We will correlate genetic determinants of tumor escape with tumor micro-environment data, including density and spatial distribution of immune cells, to map evolutionary mechanisms of treatment evasion.
DFG Programme
Collaborative Research Centres
