Collective dynamics of ion channels: statistical modeling and analysis
(B04)
Subject Area
Mathematics
Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
Term
since 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 432680300
The goal of this project is to provide a fundamental understanding of the collective behavior of multiple ion channels in lipid membranes. By combining voltage-clamp experiments and super-resolution microscopy on connexons with statistical analysis and modeling, we will address whether multiple channels act cooperatively or disruptively, and estimate the number of reconstituted channels. The results will be of great importance to unravel the mechanism and regulation of signal transmission between cells.
DFG Programme
Collaborative Research Centres
