Geometry of bio-polymer conformational dynamics (A02)

• Subject Area: Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics ; Mathematics
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 432680300

This project aims at combining state-of-the-art coarse-grained models for the stochastic dynamics of thin elastic rods with single-molecule fluorescence-spectroscopic experiments that allow for directly measuring conformational fluctuations of intrinsically disordered proteins (IDPs). The aim is to embed measurements of conformational fluctuations of IDPs into a comprehensive and powerful mathematical model that allows for connecting the experimental data with a full picture of the underlying conformational dynamics.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1456: Mathematics of Experiment: The challenge of indirect measurements in the natural sciences
• Applicant Institution: Georg-August-Universität Göttingen
• Project Heads: Professor Dr. Jörg Enderlein; Professorin Dr. Anja Sturm; Professor Dr. Max Wardetzky