Replacement purchase for a 500 MHz NMR console

• Subject Area: Biological Chemistry and Food Chemistry
• Term: Funded in 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 441546797

The research groups at the BNMRZ employ NMR spectroscopy to obtain molecular and mechanistic insight for essential biological processes that underlie physiological and diseaselinked cellular processes. The application concerns a replacement console for a 500 MHz WB solid-state NMR spectrometer. Research topics involve the analysis of protein structure and dynamics of amyloid fibrils, membrane proteins and virus assemblies. An additional focus area is the development of methods for MAS solid-state NMR. The 500 MHz spectrometer is essential for this work, as MAS solid-state NMR experiments will be implemented and tested first at low field, before experiments involving biologically interesting samples will be performed at higher magnetic field strengths.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: 500 MHz Festkörper-NMR Konsole (Teilfinanzierung)
• Instrumentation Group: 1741 Festkörper-NMR-Spektrometer
• Applicant Institution: Technische Universität München (TUM)
• Leader: Professor Dr. Bernd Reif