Process concepts for size-selective nanoparticle chromatography (B05)

• Subject Area: Chemical and Thermal Process Engineering
• Term: since 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 416229255

The objective of B05 is the development of efficient scalable processes for classification and purification of nanoparticles. We will exploit interaction chromatography to separate nanoparticles using stationary phase materials from the CRC. Tailored processes with enhanced performance are devised by model-based design and optimisation, using parameters from experiment and simulation. We focus on high-resolution schemes using advanced recycling modes and gradients, multifraction processes based on clever column arrangements per-forming simultaneously multiple fractionations and purification and, finally, novel simulated moving bed concepts for fully continuous nanoparticle classifications. The most suitable processes will be coupled to continuous particle syntheses.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1411: Design of particulate products
• Major Instrumentation: Customisable simulated moving bed (SMB) plant
• Instrumentation Group: 3500 Zellzähl- und Klassiergeräte (außer Blutanalyse), Koloniezähler
• Applicant Institution: Friedrich-Alexander-Universität Erlangen-Nürnberg
• Project Head: Professor Dr.-Ing. Malte Kaspereit