Maladaptive context inference as key mechanism underlying impaired control (B09)

• Subject Area: Biological Psychology and Cognitive Neuroscience ; Human Cognitive and Systems Neuroscience ; Cognitive, Systems and Behavioural Neurobiology
• Term: since 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 402170461

Project B09 aims to develop and empirically test a comprehensive computational model of addictive behavior. Our Bayesian Contextual Control Modell implemented in the 1st FP conceptualizes goal-directed and habitual control as context-dependent. We propose to (1) extend the current model by Pavlovian control (i.e. biased context inference and action selection), and (2) test predictions with PIT data collected during the 1st FP by B03 and a refined task. Using novel tasks developed by B09 in the 1st FP, we will (3) assess associations with SUD (alcohol and tobacco), and (4) identify neural correlates of hypothesized computational/cognitive processes using model-based fMRI.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 265: Losing and Regaining Control over Drug Intake: From Trajectories to Mechanisms to Interventions
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Project Heads: Professor Dr. Stefan Kiebel; Dr. Sarah Schwöbel, since 7/2023; Professor Dr. Michael Smolka