Defining key principles of late small ribosomal subunit assembly in archaea (B13*)

• Subject Area: Biochemistry
• Term: from 2019 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 185476941

This project proposal aims to functionally characterise the possible interplay of archaeal specific and conserved bacterial- and eukaryote-like features required for the latest steps of small ribosomal subunit synthesis in archaea. To do so, we aim to functionally characterise selected putative key trans- and cis-acting factors required for the last steps of small ribosomal subunit formation.Accordingly, this project proposal contributes to the definition of key principles of the in vivo ribosome assembly pathway in archaea and shed light on the intricate evolutionary relationship of the ribosome assembly processes.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 960: Ribosome Formation: Principles of RNP Biogenesis and Control of their Function
• Applicant Institution: Universität Regensburg
• Project Head: Professor Dr. Sébastien Ferreira-Cerca