Project Details
Formation of the repressed nanos mRNP in the early Drosophila embryo
Applicant
Professor Dr. Elmar Wahle
Subject Area
General Genetics and Functional Genome Biology
Biochemistry
Biochemistry
Term
from 2019 to 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 427447367
No abstract available
Publications
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Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Reports, 31(12), 107783.
Cao, Wen Xi; Kabelitz, Sarah; Gupta, Meera; Yeung, Eyan; Lin, Sichun; Rammelt, Christiane; Ihling, Christian; Pekovic, Filip; Low, Timothy C.H.; Siddiqui, Najeeb U.; Cheng, Matthew H.K.; Angers, Stephane; Smibert, Craig A.; Wühr, Martin; Wahle, Elmar & Lipshitz, Howard D.
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In Vitro Reconstitution of the Drosophila melanogaster CCR4-NOT Complex to Assay Deadenylation. Methods in Molecular Biology (c(2023, 10, 13)), 19-45. Springer US.
Pekovic, Filip & Wahle, Elmar
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RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system. Nucleic Acids Research, 51(8), 3950-3970.
Pekovic, Filip; Rammelt, Christiane; Kubíková, Jana; Metz, Jutta; Jeske, Mandy & Wahle, Elmar