Integrin-subtype-specific organization and force transduction (A12)

Subject Area Cell Biology
Term since 2019
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 386797833
 

Project Description

This project will investigate how the two major integrin-based adhesion complexes of epithelia, focal adhesions and hemidesmosomes, respond to mechanical signals on molecular force and length scales. Experiments will utilize recently developed technologies including tension sensor imaging, single-molecule localization microscopy and molecular Optomechanics.
DFG Programme Collaborative Research Centres
Subproject of SFB 1348:  Dynamic cellular interfaces: formation and function
Applicant Institution Universität Münster
Project Head Professor Dr. Carsten Grashoff