Insulin resistance, diabetes and metabolic liver diseases in acute myocardial infarction (B12)

• Subject Area: Cardiology, Angiology ; Endocrinology, Diabetology, Metabolism
• Term: from 2019 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 236177352

This project aims at characterizing the role of insulin resistance, typical for type 2 diabetes, in cardiac and systemic metabolism and organ crosstalk in patients with STEMI. This collaboration of cardiologists and diabetologists will enable concerted state-of-art analysis of heart function and pathogenic mechanisms (energy metabolism, inflammation) including magnetic resonance. This project has a key role within this CRC for detecting subphenotypes allowing for risk stratification of these patients with - at present - worse outcome and by serving as platform for experimental projects to identify metabolic targets for diagnostic and therapeutic interventions.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1116: Master switches in cardiac ischemia
• Applicant Institution: Heinrich-Heine-Universität Düsseldorf
• Project Heads: Professor Dr. Malte Kelm; Professor Dr. Michael Roden