Project Details
Projekt
Biofabrication of heart substitute tissue based on bioink from spider silk proteins (C01)
Subject Area
Biomaterials
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133
Heart diseases are a major socioeconomic burden. Despite considerable progress in the prevention and minimization of heart damage, the prevalence of heart insufficiency increases continuously. The aim of this subproject is the reproducible production of hierarchically organized human cardiac substitute tissue using 3D printing technology. For this purpose, hiPSC-derived cardiac cells, spider silk proteins developed during the first funding period, aligned fibers, and perfusable tubular structures will be used. The long-term goal is the treatment of heart diseases.
DFG Programme
CRC/Transregios
Applicant Institution
Julius-Maximilians-Universität Würzburg
Project Heads
Professor Dr. Felix B. Engel; Professor Dr. Thomas Scheibel
