Project Details
Projekt
Alginate-based bioinks with tailored microstructural properties for controlled cell behavior (A01)
Subject Area
Biomaterials
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133
The aim of subproject A01 is the modification of adhesive, microstructural as well as microscopic and macroscopic mechanical properties of alginate-based biofabricated hierarchical tissue analogues for controlling desired cell behavior. This goal will be achieved by adjusting the porosity through sacrificial structures and by establishing localized durotactic gradients using two-phase (core/shell) printing. By simultaneously printing bioinks with different mechanical, adhesive and structural properties that are loaded with different cell types, a high degree of complexity can be achieved to control durotaxis, cell migration, cell differentiation and tissue structure formation.
DFG Programme
CRC/Transregios
Applicant Institution
Julius-Maximilians-Universität Würzburg
Project Heads
Professor Dr.-Ing. Aldo Boccaccini; Professor Dr. Ben Fabry
