Project Details
Projekt
Identification and molecular characterization of microbe-derived PAMPs and their corresponding perception systems in Arabidopsis
Applicant
Professor Dr. Thorsten Nürnberger
Subject Area
Organismic Interactions, Chemical Ecology and Microbiomes of Plant Systems
Term
from 2007 to 2015
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 38928928
PAMP-triggered immunity (PTI) constitutes the primary or basal plant immune response. Activation of PTI is based upon the recognition of invariant patterns of microbial surfaces by plant pattern recognition receptors. Despite the identification of some microbial surface components that trigger immune responses in various plant species, non-self recognition capacities of plants are expected to reach substantially beyond current knowledge. In previous work, we have identified in fractionated Ralstonia solanacearum cell extracts peptidic fragments that trigger immunity-associated responses in Arabidopsis. These peptides will be purified to homogeneity and used to identify the corresponding plattern pattern recognition receptor.Gram-positive and Gram-negative bacteria-derived peptidoglycans (PGN) induce PTI responses in Arabidopsis. LYM3, an Arabidopsis plasma membrane protein that carries two ectopic LysM domains, has been implicated in PGN binding, PGN sensitivity and plant immunity to bacterial infection. LYM3 is a member of a small protein family comprising two additional members (LYM1, LYM2). We aim at characterizing the contribution of LYM1 and LYM2 proteins to PGN perception and to plant immunity to microbial infection.
DFG Programme
Priority Programmes
