Bifunctional hybrid nanoparticles via calcium carbonate crystallization driven by engineered protein surfaces (A07)

Subject Area Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry
Biological and Biomimetic Chemistry
Term from 2016 to 2020
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 268730352
 

Project Description

This project aims at the defined generation of structurally and functionally anisotropic nanohybrid particles of calcium carbonate and tailor-made genetically engineered proteins via non-classical pathways of crystallization. Iterative cycles of protein design and thorough investigations of their effect on in vitro calcium carbonate precipitation will identify the essential factors underlying this complex process. Eventually, this will pave the way for the rational generation of particle superstructures via directed self-assembly.
DFG Programme Collaborative Research Centres
Subproject of SFB 1214:  Anisotropic Particles as Building Blocks: Tailoring Shape, Interactions and Structures
Applicant Institution Universität Konstanz
Project Heads Professor Dr. Denis Gebauer; Professor Dr. Andreas Marx