High throughput sequencing of short DNA fragments is a powerful tool to study hematopoietic neoplasms. Sequencing with Nanopores also interrogates long native DNA and RNA and thus captures structural variations and modified nucleotides. We will provide our knowledge to perform and evaluate both short and long read high throughput sequencing. Furthermore, we will operate and expand the central IT platform of this CRC for the documentation, comparative analysis of results and visualization of various findings.
DFG Programme
Collaborative Research Centres