The role of human nucleoporins in the remodelling and export of macromolecular complexes
(P14)
Subject Area
Biochemistry
Term
from 2016 to 2019
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 264061860
The functional specialisation of subcellular compartments in eukaryotic cells requires the regulated exchange of macromolecules to establish and maintain the specific composition of each compartment. Nuclear pore complexes function as gateways between nucleus and cytoplasm and the nucleoporins interact with soluble transport receptors and cofactors during the transport of molecules and complexes. This project analyses the role of nuclear pore complexes in the remodelling and translocation of macromolecular complexes.
DFG Programme
Collaborative Research Centres
