Vergleich zwischen prähospitaler Schlaganfallversorgung in Berlin und Regelversorgung

• Antragsteller: Professor Dr. Heinrich Audebert, seit 4/2017
• Fachliche Zuordnung: Klinische Neurologie; Neurochirurgie und Neuroradiologie
• Förderung: Förderung von 2016 bis 2021
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 283917568

Pre-hospital stroke care in specialized ambulances increases thrombolysis rates, reduces alarm-to-treatment times, and improves prehospital triage. However, proof of improved functional outcome compared to usual care is still lacking. This pragmatic, prospective, blindedendpoint trial comparing functional outcomes of treatment candidates 3 months after stroke closes this gap. We will include patients whose emergency call from a predefined catchment area in Berlin, Germany, caused a stroke alarm at the dispatch center during stroke emergency mobile (STEMO) hours (7am-11pm, Monday-Sunday). STEMO is equipped with a computed tomography (CT) scanner including CT-angiography capability, point-of-care laboratory and telemedicine. A vascular neurologist, a paramedic and a radiology technician are abord. We define the primary study population as treatment candidates with a final discharge diagnosis of cerebral ischemia, onset-to-alarm time ¿ 4 hours, symptoms not resolved at time of ambulance arrival, and able to walk without assistance prior to emergency. With one STEMO per catchment area, about 40% of STEMO dispatches will be handled by regular ambulances since STEMO is already in operation for other patients. This will create a quasi-randomized control group. The results of this trial will inform decision makers on the effects of STEMO on functional outcome.

• DFG-Verfahren: Klinische Studien
• Ehemaliger Antragsteller: Privatdozent Dr. Martin Ebinger, bis 3/2017