LORE-mediated immunity in Brassicaceae (B10)

• Subject Area: Organismic Interactions, Chemical Ecology and Microbiomes of Plant Systems
• Term: from 2015 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 170483403

Cell-surface pattern recognition receptors confer resistance to a broad spectrum of pathogens. The receptor kinase LORE senses bacterial medium-chain 3-hydroxylated fatty acids (3-HFAs) in Arabidopsis thaliana and other Brassicaceae. Among the Brassicaceae, some species differ in their 3-HFA chain length-specificity and some are 3-HFA-insensitive. We will exploit the natural LORE diversity to mechanistically resolve chain-length-specific 3-HFA sensing by LORE. LORE-transgenic tomato plants will be tested for enhanced disease resistance. Additionally, we will continue our analysis of LORE activation, regulation, and downstream signalling.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 924: Molecular Mechanisms Regulating Yield and Yield Stability in Plants
• Applicant Institution: Technische Universität München (TUM)
• Project Head: Professorin Dr. Stefanie Ranf-Zipproth