GRK 804:  Analysis of Cellular Functions by Combinatorial Chemistry and Biochemistry

• Subject Area: Basic Research in Biology and Medicine ; Physical Chemistry
• Term: from 2002 to 2011
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 273495

The interdisciplinary research projects comprise modern research on medicinal substances and aim at identifying protein domains that may serve as biologically relevant targets. This shall be done by studies on structure activity relationships. Newly developed screening methods shall help to search databases for potential active substances, which are to be tested in vitro and in vivo. Combinatorial chemistry and molecular modelling will be used to facilitate the development and profiling of the medicinal substances. This interdisciplinary study programme will help the participating Ph.D. students to gain broad expertise in the life sciences including combinatorial (bio)chemistry, molecular biomedicine and pharmaceutical sciences.

• DFG Programme: Research Training Groups
• Applicant Institution: Rheinische Friedrich-Wilhelms-Universität Bonn
• Spokesperson: Professor Dr. Michael Famulok
• Participating Researchers: Professor Dr. Jürgen Bajorath; Professor Dr. Reinhard Büttner; Professor Dr. Michael Gütschow; Professor Dr. Michael Hoch; Professorin Dr. Meliha Karsak; Professor Dr. Percy Alexander Knolle; Professor Dr. Waldemar Kolanus; Professor Dr. Thomas Magin; Professorin Dr. Christa E. Müller; Professor Dr. Jörn Piel