ERA_Chemistry_Biomimetic formation and organization of magnetite nanoparticles

• Applicant: Dr. Damien Faivre
• Subject Area: Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry
• Term: from 2015 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 270108339

• Final Report Year: 2020

Final Report Abstract

In this project we produced new scientific results along the following lines: Genetically engineered mutant bacterial filaments with specifically designed functional sites on their surfaces. These filaments were then used as templates for the attachment and nucleation of magnetic nanoparticles. As such, we produced the intended materials (1D magnetic structures, in particular magnetic nanofibers), and concomitantly gained new knowledge both on the functions of the Mms6 and MamI proteins in magnetotactic bacteria and on the nucleation of crystalline nanoparticles from solutions in general. Synthesis, structural and magnetic characterization of magnetic mesocrystals and their organization. We proposed a mechanistic framework for the formation of these crystals and determined their structure / (magnetic) function relationship. In addition, we showed how the size of the particles can be varied using varying pH conditions.

Publications

• (2016) Magnetitebinding flagellar filaments displaying the MamI loop motif. ChemBioChem, 17, 2075-2082
  Bereczk-Tompa É., Pósfai M., Tóth B., Vonderviszt F.
  (See online at https://doi.org/10.1002/cbic.201600377)
• (2017) Biotemplated synthesis of magnetic filaments. Nanoscale, 9, 15062 – 15069
  Bereczk-Tompa É., Vonderviszt F., Horváth B., Szalai I., Pósfai M.
  (See online at https://doi.org/10.1039/c7nr04842d)
• (2017) Single crystalline superstructured stable single domain magnetite nanoparticles. Scientific Reports, 7, 45484
  Reichel V., Kovács A., Kumari M., Bereczk-Tompa É., Schneck E., Diehle P., Pósfai M., Hirt A.M., Duchamp M., Dunin-Borkowski R.E. and Faivre D.
  (See online at https://doi.org/10.1038/srep45484)
• (2018) Nanobody-displaying flagellar nanotubes. Scientific Reports, 8:3584
  Klein Á., Kovács M., Muskotál A., Jankovics H., Tóth B., Pósfai M., Vonderviszt F.
  (See online at https://doi.org/10.1038/s41598-018-22085-3)
• (2019), Shaping Magnetite with Poly-l-arginine and pH: From Small Single Crystals to Large Mesocrystals, J. Phys. Chem. Lett., 10 (18), 5514-5518
  Kuhrts L., Macias-Sanchez E., Tarakina N. V., Hirt A. M., and Faivre D.
  (See online at https://doi.org/10.1021/acs.jpclett.9b01771)