Functional, Metabolic and Multi-Omics phenotyping in acute myocardial infarction
(S01)
Subject Area
Anatomy and Physiology
Pharmacology
Term
from 2015 to 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 236177352
S01 provides the experimental models of ischemia/reperfusion and permanent coronary ligation using open and closed chest techniques, functional analysis by high resolution ultrasound and will train members of the CRC 1116 in surgical techniques and echocardiography. In addition a standardized diet-induced model of insulin resistance and metabolic phenotyping of mice will be provided. On the molecular level, mechanistic studies and target identification will be greatly facilitated by state-of-art proteomics, phospho-proteomics, metabolomics and lipidomics.
DFG Programme
Collaborative Research Centres
