Application of an infrared quantum cascade laser for monitoring irreversible reactions of flavin-binding light receptors and enzymes

• Applicant: Professor Dr. Tilman Kottke
• Subject Area: Biophysics
• Term: from 2015 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 266942153

• Final Report Year: 2020

Final Report Abstract

No abstract available

Publications

• A Blue-Light Photoreceptor Mediates the Feedback Regulation of Photosynthesis. Nature, Vol. 537. 2016, pp. 563–566.
  D. Petroutsos, R. Tokutsu, S. Maruyama, S. Flori, A. Greiner, L. Magneschi, L. Cusant, T. Kottke, M. Mittag, P. Hegemann, G. Finazzi, J. Minagawa
  (See online at https://doi.org/10.1038/nature19358)
• Allosteric Communication Between DNA-Binding and Light-Responsive Domains of Diatom Class I Aureochromes. Nucleic Acids Research, Vol. 44. 2016, Issue 12, pp. 5957–5970.
  A. Banerjee, E. Herman, M. Serif, M. M. Reyna, S. Hepp, R. Pokorny, P. G. Kroth, L.-O. Essen, T. Kottke
  (See online at https://doi.org/10.1093/nar/gkw420)
• Evidence for Tautomerization of Glutamine in BLUF Blue Light Receptors by Vibrational Spectroscopy and Computational Chemistry. Scientific Reports, Vol. 6. 2016, 22669.
  T. Domratcheva, E. Hartmann, I. Schlichting, T. Kottke
  (See online at https://doi.org/10.1038/srep22669)
• Chromophore-Protein Interplay during the Phytochrome Photocycle Revealed by Step-Scan FTIR Spectroscopy. Journal of the American Chemical Society, Vol. 140. 2018, Issue 39, pp.12396–12404.
  J. A. Ihalainen, E. Gustavsson, L. Schroeder, S. Donnini, H. Lehtivuori, L. Isaksson, C. Thöing, V. Modi, O. Berntsson, B. Stucki-Buchli, A. Liukkonen, H. Häkkänen, E. Kalenius, S. Westenhoff, T. Kottke
  (See online at https://doi.org/10.1021/jacs.8b04659)
• Photochemically Driven Biocatalysis of Halogenases for the Green Production of Chlorinated Compounds. ChemCatChem, Vol. 10. 2018, Issue 15, pp. 3336-3341.
  L. Schroeder, M. Frese, C. Müller, N. Sewald, T. Kottke
  (See online at https://doi.org/10.1002/cctc.201800280)
• Photoreceptors Take Charge: Emerging Principles for Light Sensing. Annual Review of Biophysics, Vol. 47. 2018, pp. 291-313.
  T. Kottke, A. Xie, D. S. Larsen, W. D. Hoff
  (See online at https://doi.org/10.1146/annurev-biophys-070317-033047)
• Single-Shot Sub-microsecond Mid-infrared Spectroscopy on Protein Reactions with Quantum Cascade Laser Frequency Combs. Analytical Chemistry, Vol. 90. 2018, Issue 17, pp. 10494–10500.
  J. L. Klocke, M. Mangold, P. Allmendinger, A. Hugi, M. Geiser, P. Jouy, J. Faist, T. Kottke
  (See online at https://doi.org/10.1021/acs.analchem.8b02531)
• Arguments for an Additional Long-lived Intermediate in the Photocycle of the Full-length Aureochrome 1c Receptor: a Time-resolved Small-angle X-ray Scattering Study. Structural Dynamics, Vol. 6. 2019, 034701.
  S. Bannister, E. Böhm, T. Zinn, T. Hellweg, T. Kottke
  (See online at https://doi.org/10.1063/1.5095063)
• Swelling Behaviour of Core‐Shell Microgels in H2O, Analysed by Temperature‐Dependent FTIR Spectroscopy. Physical Chemistry Chemical Physics, Vol. 21. 2019, Issue 2, pp. 572-580.
  L. Wiehemeier, M. Cors, O. Wrede, J. Oberdisse, T. Hellweg, T. Kottke
  (See online at https://doi.org/10.1039/c8cp05911j)
• Time-resolved Infrared and Visible Spectroscopy on Cryptochrome aCRY: Basis for Red Light Reception. Biophysical Journal, Vol. 117. 2019, Issue 3, pp. 490-499.
  S. Oldemeyer, M. Mittag, T. Kottke
  (See online at https://doi.org/10.1016/j.bpj.2019.06.027)