The molecular basis of maintaining genome integrity in the mammalian germline during meiosis

No abstract available

Publications

• Alignment of homologous chromosomes and effective repair of programmed DNA double-strand breaks during mouse meiosis require the minichromosome maintenance domain containing 2 (MCMDC2) protein. PLoS Genetics, Vol. 12. 2016, Issue 10, e1006393.
  Finsterbusch F., Ravindranathan R., Dereli I., Stanzione M., Tränkner D., Tóth A.
  
• Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nature Cell Biology, Vol. 18. 2016, pp. 1208–1220.
  Stanzione M., Baumann M., Papanikos F., Dereli I., Lange J., Ramlal A., Tränkner D., Shibuya H., de Massy B., Watanabe Y., Jasin M., Keeney S., Tóth A.
  
• The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice. Chromosoma, Vol. 126. 2017, Issue 3, pp. 399-415.
  Papanikos F., Daniel K., Goercharn-Ramlal A., Fei J.F., Kurth T., Wojtasz L., Dereli I., Fu J., Penninger J., Habermann B., Surani A., Stewart A.F., Tóth A.
  
• Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. Molecular Cell, Vol. 74. 2019, Issue 5, pp. 1069-1085.e11.
  Papanikos F., Clément J.A.J., Testa E., Ravindranathan R,. Grey C., Dereli I., Bondarieva A., Valerio-Cabrera S., Stanzione M., Schleiffer A., Jansa P., Lustyk D., Fei J.F., Adams I.R., Forejt J., Barchi M., de Massy B., Tóth A.
  
• Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Nature Communications, Vol. 11. 2020, Article number: 3101.
  Bondarieva A., Raveendran K., Telychko V., Rao P.H.B.D., Ravindranathan R., Zorzompokou C., Finsterbusch F., Dereli I., Papanikos F., Tränkner D., Schleiffer A., Fei J.F., Klimova A., Ito M., Dhananjaya S., Kulkarni D.S., Roeder I., Hunter N., Tóth A.
  
• Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice. Nucleic Acids Research, Vol. 49. 2021, Issue 5, pp. 2609–2628.
  Dereli I., Stanzione M., Olmeda F., Papanikos F., Baumann M., Demir S, Carofiglio F., Lange J., de Massy B., Baarends W.M., Turner J., Rulands S., Tóth A.