Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS) Core Facility (S01)

• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 2014 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 236360313

The service project, S01, connects the mass spectrometry platforms of Internal Medicine I and the Centre for Organismal Studies with the aim of providing consortium members the means to perform quantitative analysis of reactive metabolites, and their associated post-translational modifications, in relation to changes in core metabolism. The implementation of novel protocols and metabolomics techniques, such as 13C/15N tracing, will be a major focus for the future research program, thereby providing the prerequisites for translational applications.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1118: Reactive metabolites as a cause of diabetes complications
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Project Heads: Dr. Thomas Henry Fleming; Professor Dr. Rüdiger Hell, since 7/2018