Epigenetic mechanisms during pathogen-specific mastitis of the cow

Applicants Dr. Juliane Günther; Privatdozent Dr. Wolfram Petzl

Subject Area Veterinary Medical Science

Term from 2014 to 2019

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 251480024

Final Report Year 2020

Final Report Abstract

No abstract available

Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection. Sci Rep. 2017; 6;7(1):4811
Günther J, Petzl W, Bauer I, Ponsuksili S, Zerbe H, Schuberth HJ, Brunner RM, Seyfert HM
(See online at https://doi.org/10.1038/s41598-017-05107-4)
TLR ligands, but not modulators of histone modifiers, can induce the complex immune response pattern of endotoxin tolerance in mammary epithelial cells. Innate Immun. 2017; 23(2):155-164
Günther J, Petzl W, Zerbe H, Schuberth HJ, Seyfert HM
(See online at https://doi.org/10.1177/1753425916681076)
Pathogen-specific responses in the bovine udder. Models and immunoprophylactic concepts. Res Vet Sci. 2018 Feb;116:55-61
Petzl W, Zerbe H, Günther J, Seyfert HM, Hussen J, Schuberth HJ
(See online at https://doi.org/10.1016/j.rvsc.2017.12.012)
The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells. Immunopathol. 2018; 40:555–565
Günther J, Seyfert HM
(See online at https://doi.org/10.1007/s00281-018-0701-1)
Untersuchungen in vitro zu epigenetisch wirksamen Immunmodulatoren bei der Pathogen-spezifischen Mastitis des Rindes
Laura E. Macías Luaces
(See online at https://doi.org/10.5282/edoc.24134)