Project Details
Projekt
Metrology for biomedical applications of magnetic hybrid materials
Applicant
Dr. Frank Wiekhorst
Subject Area
Fluid Mechanics
Experimental Condensed Matter Physics
Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
Experimental Condensed Matter Physics
Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
Term
from 2013 to 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 238061145
The aim of the project is the development and application of magnetic measurement procedures based on magnetorelaxometry (MRX) and magnetic particle spectroscopy (MPS), and magnetic particle imaging (MPI), that will enable to describe quantitatively the particle matrix interaction, in particular in the presence of additional magnetic fields and in flowing media. We will focus primarily on physically well-defined magnetic hybrid materials in order to relate the measured magnetic parameters to the relevant interaction parameters. These hybrid materials shall serve as models to describe the particle Matrix interaction in the far more complex biomedical application settings such as hyperthermia, magnetic thermoablation, contrast agent in imaging (MRI, MPI), magnetic drug targeting or magnetofection using magnetic nanoparticles. In the final stage, the developed magnetic measurement procedures shall enable the assessment of the interaction of magnetic nanoparticles with their biological matrix in the above mentionedin-vivo applications.
DFG Programme
Priority Programmes
