REDOX-mediated modulation of immune stimulation by Toll-like receptors (TLR)

• Applicant: Professor Dr. Martin Röcken
• Subject Area: Dermatology ; Immunology
• Term: from 2013 to 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 234582253

• Final Report Year: 2021

Final Report Abstract

No abstract available

Publications

• Cholesterol Modification of p40-Specific Small Interfering RNA Enables Therapeutic Targeting of Dendritic Cells. Journal of Immunology, Vol. 195. 2015, Issue 5, pp. 2216-2223.
  Jürgen Brück, Steve Pascolo, Kerstin Fuchs, Christina Kellerer, Ivana Glocova, Julia Geisel, Katja Dengler, Amir S. Yazdi, Martin Röcken and Kamran Ghoreschi
  (See online at https://doi.org/10.4049/jimmunol.1402989)
• IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells. PNAS, Vol. 112. 2015, No. 7, pp. 2163–2168.
  Emmanuella Guenova, Yuliya Skabytska, Wolfram Hoetzenecker, Tilo Biedermann et al.
  (See online at https://doi.org/10.1073/pnas.1416922112)
• Cutaneous immunology: basics and new concepts. Seminars in Immunopathology, Vol. 38. 2016, pp. 3–10.
  Yazdi, A.S., Röcken, M., Ghoreschi, K.
  (See online at https://doi.org/10.1007/s00281-015-0545-x)
• Methyl Fumarate-Derived Iron Carbonyl Complexes (FumET-CORMs) as Powerful Anti-inflammatory Agents. ChemMedChem, Vol. 12. 2017, Issue 23, pp. 1927-1930.
  Britta Bauer, Anna-Lena Göderz, Heidi Braumüller, Jörg Martin Neudörfl, Martin Röcken et al.
  (See online at https://doi.org/10.1002/cmdc.201700488)
• Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation. Scientific Reports, Vol. 7. 2017, Article number: 44482.
  Brück, J., Holstein, J., Glocova, I. et al.
  (See online at https://doi.org/10.1038/srep44482)
• Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell–Driven Inflammation. Molecular Imaging and Biology, Vol. 22. 2020, pp. 504–514.
  Schwenck, J., Mehling, R., Thaiss, W.M. et al.
  (See online at https://doi.org/10.1007/s11307-019-01412-8)