Surface designs for the control of cell migration (B01)

• Subject Area: Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
• Term: from 2012 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 201269156

Project B01 develops micro- and nanostructured arrays, such as two-state patterns, that allow for the investigation of single migrating cells and two-cell interactions in confinement. A major goal is to describe dynamic phenotypes using mechanistic models of intracellular reaction-diffusion dynamics and to connect these to cancer-specific expression of microRNA (miR-200c) and the curvature sensitive myosin motor, myo6.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1032: Nanoagents for Spatio-temporal Control of Molecular and Cellular Reactions
• Applicant Institution: Ludwig-Maximilians-Universität München
• Project Heads: Professor Dr. Joachim Rädler; Professorin Dr. Claudia Veigel, since 7/2020