Anisometric microgels to construct 3D responsive macroporous matrices to direct and mechanically trigger cells (B05)

• Subject Area: Preparatory and Physical Chemistry of Polymers
• Term: from 2012 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 191948804

3D macroporous, responsive constructs are created via anisometric microgel assembly to actuate cells. The internal structure (nanoporosity), mechanical properties, and photo-thermal or magnetic responsiveness of the microgel building blocks will be characterized and optimized for cell culture. The assembly of microgels with complex and rod shapes will provide 3D macroporous, responsive matrices to support and guide cell growth and provide native-like environments. Depending on the network’s properties, microgels’ chemical composition, loaded nanoparticles, and swelling properties, cells will be actuated by the network and studied in response to external triggers, such as light and magnetic fields.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 985: Functional Microgels and Microgel Systems
• Applicant Institution: Rheinisch-Westfälische Technische Hochschule Aachen
• Project Heads: Professor Jérôme Crassous, Ph.D.; Professorin Dr.-Ing. Laura De Laporte, since 7/2016; Professor Dr. Martin Möller, until 6/2016; Professorin Dr. Olga Vinogradova, until 6/2016; Professor Dr.-Ing. Matthias Wessling