Investigation of nesfatin-1 as a peptide product of the gastric X/A-like cell on anxiety behavior in animals and humans.

• Applicant: Professor Dr. Andreas Stengel
• Subject Area: Endocrinology, Diabetology, Metabolism ; Nutritional Sciences ; Gastroenterology
• Term: from 2012 to 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 216245554

This project will focus on a peptide hormone that is not only involved in the regulation of food intake (as a so called satiety hormone) but also plays a role in the stress axis. Recent studies showed that this hormone, nesfatin-1, has an anxiogenic effect in animals and also shows an association with anxiety in humans. The studies proposed here will further investigate the topic of the role of nesfatin-1, predominantly the acute regulation, in the mediation of anxiety in animals and humans.

• DFG Programme: Research Grants